Physical Properties | | | |
Molecular Weight: 414.44 g/mol | logS: -4.96119 | SlogP: 4.79347 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0580744 | Sterimol/B1: 2.85824 | Sterimol/B2: 4.61921 | Sterimol/B3: 5.21622 |
Sterimol/B4: 7.0529 | Sterimol/L: 18.0462 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 662.567 | Positive charged surface: 388.794 | Negative charged surface: 269.054 | Volume: 382.5 |
Hydrophobic surface: 555.605 | Hydrophilic surface: 106.962 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 0 | |