Physical Properties | | | |
Molecular Weight: 378.924 g/mol | logS: -4.66434 | SlogP: 4.35002 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.151366 | Sterimol/B1: 2.27502 | Sterimol/B2: 2.47316 | Sterimol/B3: 6.6278 |
Sterimol/B4: 6.82345 | Sterimol/L: 17.3167 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 604.253 | Positive charged surface: 305.1 | Negative charged surface: 299.153 | Volume: 346.75 |
Hydrophobic surface: 529.944 | Hydrophilic surface: 74.309 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |