Physical Properties | | | |
Molecular Weight: 418.924 g/mol | logS: -6.02891 | SlogP: 6.5203 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0995611 | Sterimol/B1: 2.16213 | Sterimol/B2: 4.93174 | Sterimol/B3: 6.15142 |
Sterimol/B4: 6.6879 | Sterimol/L: 17.6407 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 671.938 | Positive charged surface: 362.198 | Negative charged surface: 305.41 | Volume: 401.875 |
Hydrophobic surface: 567.459 | Hydrophilic surface: 104.479 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |