Physical Properties | | | |
Molecular Weight: 390.443 g/mol | logS: -4.44155 | SlogP: 3.3087 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0540453 | Sterimol/B1: 2.28316 | Sterimol/B2: 5.78571 | Sterimol/B3: 5.86916 |
Sterimol/B4: 6.47132 | Sterimol/L: 18.0163 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 670.085 | Positive charged surface: 450.574 | Negative charged surface: 213.824 | Volume: 375.875 |
Hydrophobic surface: 529.875 | Hydrophilic surface: 140.21 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |