Physical Properties | | | |
Molecular Weight: 394.862 g/mol | logS: -5.12546 | SlogP: 3.9535 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0712536 | Sterimol/B1: 2.24259 | Sterimol/B2: 5.64217 | Sterimol/B3: 5.80354 |
Sterimol/B4: 6.60901 | Sterimol/L: 16.7641 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 634.51 | Positive charged surface: 367.102 | Negative charged surface: 261.529 | Volume: 363.875 |
Hydrophobic surface: 509.451 | Hydrophilic surface: 125.059 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |