Physical Properties | | | |
Molecular Weight: 395.507 g/mol | logS: -3.35992 | SlogP: 2.8087 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0491162 | Sterimol/B1: 3.10039 | Sterimol/B2: 3.89388 | Sterimol/B3: 4.49327 |
Sterimol/B4: 8.0862 | Sterimol/L: 19.0584 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 727.869 | Positive charged surface: 457.611 | Negative charged surface: 270.258 | Volume: 402.125 |
Hydrophobic surface: 558.766 | Hydrophilic surface: 169.103 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |