Physical Properties | | | |
Molecular Weight: 402.494 g/mol | logS: -5.98021 | SlogP: 5.99506 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0629176 | Sterimol/B1: 2.70317 | Sterimol/B2: 3.39101 | Sterimol/B3: 5.05708 |
Sterimol/B4: 8.87702 | Sterimol/L: 19.9227 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 718.894 | Positive charged surface: 431.997 | Negative charged surface: 281.764 | Volume: 405.25 |
Hydrophobic surface: 606.104 | Hydrophilic surface: 112.79 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |