Physical Properties | | | |
Molecular Weight: 414.505 g/mol | logS: -5.49171 | SlogP: 5.79382 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0599177 | Sterimol/B1: 2.31918 | Sterimol/B2: 3.41139 | Sterimol/B3: 4.32455 |
Sterimol/B4: 10.1351 | Sterimol/L: 19.4176 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 713.756 | Positive charged surface: 456.644 | Negative charged surface: 253.187 | Volume: 416.25 |
Hydrophobic surface: 605.105 | Hydrophilic surface: 108.651 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |