Physical Properties | | | |
Molecular Weight: 421.521 g/mol | logS: -3.88299 | SlogP: 3.7485 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.159156 | Sterimol/B1: 2.58311 | Sterimol/B2: 4.40065 | Sterimol/B3: 5.69761 |
Sterimol/B4: 8.78473 | Sterimol/L: 17.2259 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 662.368 | Positive charged surface: 466.352 | Negative charged surface: 196.016 | Volume: 396.875 |
Hydrophobic surface: 596.874 | Hydrophilic surface: 65.494 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |