Physical Properties | | | |
Molecular Weight: 411.542 g/mol | logS: -5.98458 | SlogP: 5.47362 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0614753 | Sterimol/B1: 2.16319 | Sterimol/B2: 3.6324 | Sterimol/B3: 4.13546 |
Sterimol/B4: 7.74531 | Sterimol/L: 18.1209 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 659.258 | Positive charged surface: 489.022 | Negative charged surface: 165.836 | Volume: 405.875 |
Hydrophobic surface: 568.255 | Hydrophilic surface: 91.003 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 3 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |