Physical Properties | | | |
Molecular Weight: 418.521 g/mol | logS: -5.44611 | SlogP: 4.88342 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0740917 | Sterimol/B1: 2.36529 | Sterimol/B2: 3.28279 | Sterimol/B3: 5.23439 |
Sterimol/B4: 9.92853 | Sterimol/L: 18.6676 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 697.195 | Positive charged surface: 441.216 | Negative charged surface: 255.979 | Volume: 392.875 |
Hydrophobic surface: 534.079 | Hydrophilic surface: 163.116 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |