Physical Properties | | | |
Molecular Weight: 421.518 g/mol | logS: -4.43081 | SlogP: 2.5146 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.175139 | Sterimol/B1: 2.06219 | Sterimol/B2: 3.41406 | Sterimol/B3: 7.51885 |
Sterimol/B4: 8.47818 | Sterimol/L: 17.7566 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 701.145 | Positive charged surface: 464.366 | Negative charged surface: 236.779 | Volume: 388.25 |
Hydrophobic surface: 480.273 | Hydrophilic surface: 220.872 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |