Physical Properties | | | |
Molecular Weight: 412.369 g/mol | logS: -4.35017 | SlogP: 0.8801 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0245683 | Sterimol/B1: 2.42508 | Sterimol/B2: 2.71976 | Sterimol/B3: 4.20201 |
Sterimol/B4: 6.83319 | Sterimol/L: 19.798 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 624.35 | Positive charged surface: 307.011 | Negative charged surface: 291.613 | Volume: 328.375 |
Hydrophobic surface: 371.886 | Hydrophilic surface: 252.464 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |