Physical Properties | | | |
Molecular Weight: 412.369 g/mol | logS: -4.35017 | SlogP: 0.8801 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.100284 | Sterimol/B1: 2.32033 | Sterimol/B2: 4.17625 | Sterimol/B3: 4.35305 |
Sterimol/B4: 8.06615 | Sterimol/L: 16.6765 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 616.575 | Positive charged surface: 300.505 | Negative charged surface: 281.887 | Volume: 327.625 |
Hydrophobic surface: 378.441 | Hydrophilic surface: 238.134 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |