Physical Properties | | | |
Molecular Weight: 405.458 g/mol | logS: -4.91298 | SlogP: 4.2044 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0411408 | Sterimol/B1: 2.26385 | Sterimol/B2: 3.6967 | Sterimol/B3: 5.7108 |
Sterimol/B4: 6.35402 | Sterimol/L: 21.9029 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 698.377 | Positive charged surface: 479.521 | Negative charged surface: 212.77 | Volume: 383.5 |
Hydrophobic surface: 575.217 | Hydrophilic surface: 123.16 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |