Physical Properties | | | |
Molecular Weight: 393.531 g/mol | logS: -3.8461 | SlogP: 3.16351 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0325437 | Sterimol/B1: 2.80948 | Sterimol/B2: 3.26448 | Sterimol/B3: 3.67788 |
Sterimol/B4: 5.70421 | Sterimol/L: 22.0292 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 698.707 | Positive charged surface: 485.505 | Negative charged surface: 213.201 | Volume: 402.875 |
Hydrophobic surface: 616.246 | Hydrophilic surface: 82.461 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |