Physical Properties | | | |
Molecular Weight: 420.9 g/mol | logS: -6.84855 | SlogP: 5.05194 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.238431 | Sterimol/B1: 2.31458 | Sterimol/B2: 5.35668 | Sterimol/B3: 5.54593 |
Sterimol/B4: 9.46349 | Sterimol/L: 14.5712 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 636.418 | Positive charged surface: 344.836 | Negative charged surface: 291.582 | Volume: 388.625 |
Hydrophobic surface: 449.007 | Hydrophilic surface: 187.411 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |