Physical Properties | | | |
Molecular Weight: 411.505 g/mol | logS: -6.8162 | SlogP: 3.8072 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.117633 | Sterimol/B1: 2.44618 | Sterimol/B2: 5.00571 | Sterimol/B3: 6.62567 |
Sterimol/B4: 7.20644 | Sterimol/L: 17.0969 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 630.778 | Positive charged surface: 345.059 | Negative charged surface: 285.72 | Volume: 378.25 |
Hydrophobic surface: 488.789 | Hydrophilic surface: 141.989 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |