Physical Properties | | | |
Molecular Weight: 408.453 g/mol | logS: -4.54595 | SlogP: 2.32147 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0675784 | Sterimol/B1: 2.3816 | Sterimol/B2: 3.72453 | Sterimol/B3: 3.92419 |
Sterimol/B4: 8.34656 | Sterimol/L: 18.9503 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 653.044 | Positive charged surface: 404.138 | Negative charged surface: 244.708 | Volume: 387.5 |
Hydrophobic surface: 546.053 | Hydrophilic surface: 106.991 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 1 | Acid groups: 2 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |