Physical Properties | | | |
Molecular Weight: 380.4 g/mol | logS: -4.43151 | SlogP: 3.59357 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0992804 | Sterimol/B1: 3.17192 | Sterimol/B2: 3.68506 | Sterimol/B3: 4.19122 |
Sterimol/B4: 7.56178 | Sterimol/L: 16.5582 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 644.514 | Positive charged surface: 421.085 | Negative charged surface: 219.603 | Volume: 355.25 |
Hydrophobic surface: 495.155 | Hydrophilic surface: 149.359 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |