Physical Properties | | | |
Molecular Weight: 416.477 g/mol | logS: -8.40499 | SlogP: 5.5154 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0171199 | Sterimol/B1: 2.50722 | Sterimol/B2: 4.18055 | Sterimol/B3: 4.54993 |
Sterimol/B4: 8.23963 | Sterimol/L: 21.0771 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 731.968 | Positive charged surface: 453.62 | Negative charged surface: 278.348 | Volume: 404 |
Hydrophobic surface: 556.503 | Hydrophilic surface: 175.465 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |