Physical Properties | | | |
Molecular Weight: 407.474 g/mol | logS: -5.05875 | SlogP: 3.1756 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.130312 | Sterimol/B1: 2.46322 | Sterimol/B2: 2.59203 | Sterimol/B3: 5.08947 |
Sterimol/B4: 9.87544 | Sterimol/L: 14.9821 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 627.949 | Positive charged surface: 452.912 | Negative charged surface: 169.961 | Volume: 387.5 |
Hydrophobic surface: 479.465 | Hydrophilic surface: 148.484 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |