Physical Properties | | | |
Molecular Weight: 395.483 g/mol | logS: -4.2885 | SlogP: 2.83307 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.167778 | Sterimol/B1: 1.98848 | Sterimol/B2: 3.66169 | Sterimol/B3: 6.31887 |
Sterimol/B4: 7.20488 | Sterimol/L: 15.217 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 578.824 | Positive charged surface: 348.362 | Negative charged surface: 226.735 | Volume: 358.625 |
Hydrophobic surface: 492.163 | Hydrophilic surface: 86.661 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |