Physical Properties | | | |
Molecular Weight: 432.588 g/mol | logS: -6.49838 | SlogP: 3.63256 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0555076 | Sterimol/B1: 2.57063 | Sterimol/B2: 3.0749 | Sterimol/B3: 4.88832 |
Sterimol/B4: 11.8586 | Sterimol/L: 18.8972 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 808.259 | Positive charged surface: 559.996 | Negative charged surface: 248.263 | Volume: 455 |
Hydrophobic surface: 715.858 | Hydrophilic surface: 92.401 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |