Physical Properties | | | |
Molecular Weight: 404.43 g/mol | logS: -4.58486 | SlogP: 2.66412 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.047749 | Sterimol/B1: 1.969 | Sterimol/B2: 3.60571 | Sterimol/B3: 4.29701 |
Sterimol/B4: 9.37421 | Sterimol/L: 17.9762 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 690.553 | Positive charged surface: 430.31 | Negative charged surface: 260.243 | Volume: 374 |
Hydrophobic surface: 518.927 | Hydrophilic surface: 171.626 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |