Physical Properties | | | |
Molecular Weight: 423.516 g/mol | logS: -7.26754 | SlogP: 5.77982 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0605874 | Sterimol/B1: 3.45633 | Sterimol/B2: 4.42026 | Sterimol/B3: 5.85373 |
Sterimol/B4: 7.71905 | Sterimol/L: 18.7435 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 735.336 | Positive charged surface: 463.39 | Negative charged surface: 271.946 | Volume: 419.625 |
Hydrophobic surface: 624.616 | Hydrophilic surface: 110.72 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |