Physical Properties | | | |
Molecular Weight: 416.477 g/mol | logS: -6.70507 | SlogP: 4.8161 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0431434 | Sterimol/B1: 3.06852 | Sterimol/B2: 4.30331 | Sterimol/B3: 4.85115 |
Sterimol/B4: 8.33383 | Sterimol/L: 17.5684 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 678.239 | Positive charged surface: 441.561 | Negative charged surface: 236.677 | Volume: 393.75 |
Hydrophobic surface: 565.553 | Hydrophilic surface: 112.686 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 0 | |