Physical Properties | | | |
Molecular Weight: 421.453 g/mol | logS: -5.33305 | SlogP: 3.2409 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0717595 | Sterimol/B1: 3.10763 | Sterimol/B2: 4.13957 | Sterimol/B3: 4.1553 |
Sterimol/B4: 10.7394 | Sterimol/L: 16.6525 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 692.161 | Positive charged surface: 482.672 | Negative charged surface: 203.79 | Volume: 385 |
Hydrophobic surface: 539.229 | Hydrophilic surface: 152.932 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |