Physical Properties | | | |
Molecular Weight: 410.477 g/mol | logS: -7.15175 | SlogP: 5.1144 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0630927 | Sterimol/B1: 1.99917 | Sterimol/B2: 2.5022 | Sterimol/B3: 5.04436 |
Sterimol/B4: 10.5354 | Sterimol/L: 16.5921 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 711.376 | Positive charged surface: 442.978 | Negative charged surface: 268.398 | Volume: 396 |
Hydrophobic surface: 594.22 | Hydrophilic surface: 117.156 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |