Physical Properties | | | |
Molecular Weight: 421.497 g/mol | logS: -4.51037 | SlogP: 2.768 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.046694 | Sterimol/B1: 2.14559 | Sterimol/B2: 3.21257 | Sterimol/B3: 5.37264 |
Sterimol/B4: 8.04517 | Sterimol/L: 21.1711 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 712.73 | Positive charged surface: 491.983 | Negative charged surface: 220.747 | Volume: 406.625 |
Hydrophobic surface: 595.626 | Hydrophilic surface: 117.104 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |