Physical Properties | | | |
Molecular Weight: 389.475 g/mol | logS: -4.04183 | SlogP: 1.95207 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0210299 | Sterimol/B1: 2.05663 | Sterimol/B2: 3.27213 | Sterimol/B3: 3.61766 |
Sterimol/B4: 7.42818 | Sterimol/L: 23.0238 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 724.498 | Positive charged surface: 524.297 | Negative charged surface: 200.201 | Volume: 377.5 |
Hydrophobic surface: 599.546 | Hydrophilic surface: 124.952 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |