Physical Properties | | | |
Molecular Weight: 388.487 g/mol | logS: -4.82558 | SlogP: 3.29247 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0267853 | Sterimol/B1: 2.15282 | Sterimol/B2: 2.21263 | Sterimol/B3: 5.1423 |
Sterimol/B4: 6.82488 | Sterimol/L: 23.3425 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 710.732 | Positive charged surface: 499.232 | Negative charged surface: 211.501 | Volume: 385 |
Hydrophobic surface: 576.676 | Hydrophilic surface: 134.056 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |