Physical Properties | | | |
Molecular Weight: 376.219 g/mol | logS: -6.03151 | SlogP: 3.32779 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0809859 | Sterimol/B1: 2.68383 | Sterimol/B2: 4.66978 | Sterimol/B3: 5.02429 |
Sterimol/B4: 6.35517 | Sterimol/L: 16.5009 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 578.573 | Positive charged surface: 254.863 | Negative charged surface: 318.843 | Volume: 318.625 |
Hydrophobic surface: 464.736 | Hydrophilic surface: 113.837 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 1 | Acid groups: 2 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |