Physical Properties | | | |
Molecular Weight: 418.541 g/mol | logS: -5.07666 | SlogP: 4.04734 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0192453 | Sterimol/B1: 2.85494 | Sterimol/B2: 3.35419 | Sterimol/B3: 3.43286 |
Sterimol/B4: 10.0237 | Sterimol/L: 21.3966 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 751.617 | Positive charged surface: 534.411 | Negative charged surface: 211.645 | Volume: 418.75 |
Hydrophobic surface: 673.552 | Hydrophilic surface: 78.065 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |