Physical Properties | | | |
Molecular Weight: 409.533 g/mol | logS: -7.03011 | SlogP: 5.82166 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0267193 | Sterimol/B1: 2.30293 | Sterimol/B2: 3.46411 | Sterimol/B3: 3.77335 |
Sterimol/B4: 11.7183 | Sterimol/L: 21.4339 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 746.078 | Positive charged surface: 446.804 | Negative charged surface: 293.705 | Volume: 418.875 |
Hydrophobic surface: 666.149 | Hydrophilic surface: 79.929 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |