Physical Properties | | | |
Molecular Weight: 423.513 g/mol | logS: -5.15072 | SlogP: 4.5405 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0278351 | Sterimol/B1: 3.03891 | Sterimol/B2: 4.31601 | Sterimol/B3: 4.3335 |
Sterimol/B4: 9.92158 | Sterimol/L: 22.4857 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 777.902 | Positive charged surface: 566.843 | Negative charged surface: 205.359 | Volume: 419.5 |
Hydrophobic surface: 644.74 | Hydrophilic surface: 133.162 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |