Physical Properties | | | |
Molecular Weight: 391.471 g/mol | logS: -5.10781 | SlogP: 4.668 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0539899 | Sterimol/B1: 2.49956 | Sterimol/B2: 5.18876 | Sterimol/B3: 6.45835 |
Sterimol/B4: 6.58303 | Sterimol/L: 18.815 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 691.164 | Positive charged surface: 499.052 | Negative charged surface: 186.442 | Volume: 381.875 |
Hydrophobic surface: 613.11 | Hydrophilic surface: 78.054 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |