Physical Properties | | | |
Molecular Weight: 378.476 g/mol | logS: -4.37305 | SlogP: 3.74597 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0663566 | Sterimol/B1: 2.26001 | Sterimol/B2: 2.79224 | Sterimol/B3: 4.74588 |
Sterimol/B4: 12.0524 | Sterimol/L: 16.9448 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 684.741 | Positive charged surface: 498.975 | Negative charged surface: 185.766 | Volume: 376.5 |
Hydrophobic surface: 599.631 | Hydrophilic surface: 85.11 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |