Physical Properties | | | |
Molecular Weight: 418.472 g/mol | logS: -4.69442 | SlogP: 3.7428 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0684415 | Sterimol/B1: 2.34999 | Sterimol/B2: 3.72551 | Sterimol/B3: 4.4107 |
Sterimol/B4: 8.07426 | Sterimol/L: 18.9937 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 655.753 | Positive charged surface: 420.857 | Negative charged surface: 234.896 | Volume: 387.125 |
Hydrophobic surface: 566.039 | Hydrophilic surface: 89.714 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |