Physical Properties | | | |
Molecular Weight: 377.464 g/mol | logS: -6.01636 | SlogP: 3.64047 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.109439 | Sterimol/B1: 2.18649 | Sterimol/B2: 3.84813 | Sterimol/B3: 6.04722 |
Sterimol/B4: 9.27263 | Sterimol/L: 17.4626 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 663.536 | Positive charged surface: 400.163 | Negative charged surface: 259.914 | Volume: 382.375 |
Hydrophobic surface: 484.683 | Hydrophilic surface: 178.853 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 1 | Acid groups: 2 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |