Physical Properties | | | |
Molecular Weight: 404.514 g/mol | logS: -4.81458 | SlogP: 3.48479 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0281533 | Sterimol/B1: 2.80274 | Sterimol/B2: 3.14004 | Sterimol/B3: 4.68285 |
Sterimol/B4: 7.6539 | Sterimol/L: 21.5743 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 719.263 | Positive charged surface: 551.718 | Negative charged surface: 162.875 | Volume: 402.5 |
Hydrophobic surface: 644.543 | Hydrophilic surface: 74.72 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |