Physical Properties | | | |
Molecular Weight: 453.542 g/mol | logS: -5.80928 | SlogP: 5.5809 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.101105 | Sterimol/B1: 4.76011 | Sterimol/B2: 5.4646 | Sterimol/B3: 5.46956 |
Sterimol/B4: 7.32557 | Sterimol/L: 20.3065 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 748.753 | Positive charged surface: 490.871 | Negative charged surface: 253.919 | Volume: 444.625 |
Hydrophobic surface: 668.403 | Hydrophilic surface: 80.35 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |