Physical Properties | | | |
Molecular Weight: 408.586 g/mol | logS: -4.24227 | SlogP: 4.9983 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.245334 | Sterimol/B1: 3.96196 | Sterimol/B2: 4.86653 | Sterimol/B3: 5.62461 |
Sterimol/B4: 8.7984 | Sterimol/L: 16.0787 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 662.589 | Positive charged surface: 484.415 | Negative charged surface: 178.174 | Volume: 426.625 |
Hydrophobic surface: 595.769 | Hydrophilic surface: 66.82 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 3 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |