Physical Properties | | | |
Molecular Weight: 491.544 g/mol | logS: -4.48896 | SlogP: 4.3345 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.277809 | Sterimol/B1: 2.37404 | Sterimol/B2: 2.56353 | Sterimol/B3: 7.70373 |
Sterimol/B4: 10.7623 | Sterimol/L: 17.3619 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 746.741 | Positive charged surface: 577.61 | Negative charged surface: 169.131 | Volume: 456.375 |
Hydrophobic surface: 668.85 | Hydrophilic surface: 77.891 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 7 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 0 | |