Physical Properties | | | |
Molecular Weight: 482.537 g/mol | logS: -2.78 | SlogP: 2.4055 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.184472 | Sterimol/B1: 3.80886 | Sterimol/B2: 5.43756 | Sterimol/B3: 5.92795 |
Sterimol/B4: 6.88904 | Sterimol/L: 19.8542 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 758.931 | Positive charged surface: 597.554 | Negative charged surface: 161.377 | Volume: 452.375 |
Hydrophobic surface: 624.479 | Hydrophilic surface: 134.452 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 0 | |