Physical Properties | | | |
Molecular Weight: 469.9 g/mol | logS: -5.11967 | SlogP: 4.536 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.306623 | Sterimol/B1: 2.38299 | Sterimol/B2: 2.52185 | Sterimol/B3: 7.39707 |
Sterimol/B4: 9.7188 | Sterimol/L: 16.4542 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 700.851 | Positive charged surface: 452.728 | Negative charged surface: 248.123 | Volume: 411.5 |
Hydrophobic surface: 621.149 | Hydrophilic surface: 79.702 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 0 | |