Physical Properties | | | |
Molecular Weight: 402.494 g/mol | logS: -5.06481 | SlogP: 5.213 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0888596 | Sterimol/B1: 3.05783 | Sterimol/B2: 4.70019 | Sterimol/B3: 5.09998 |
Sterimol/B4: 9.2169 | Sterimol/L: 15.9112 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 675.604 | Positive charged surface: 439.313 | Negative charged surface: 236.291 | Volume: 401.5 |
Hydrophobic surface: 591.784 | Hydrophilic surface: 83.82 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |