Physical Properties | | | |
Molecular Weight: 425.548 g/mol | logS: -4.64708 | SlogP: 4.2664 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0783277 | Sterimol/B1: 2.21141 | Sterimol/B2: 3.51834 | Sterimol/B3: 6.35491 |
Sterimol/B4: 8.54171 | Sterimol/L: 17.0325 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 754.399 | Positive charged surface: 471.765 | Negative charged surface: 282.634 | Volume: 429.875 |
Hydrophobic surface: 640.572 | Hydrophilic surface: 113.827 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |