Physical Properties | | | |
Molecular Weight: 404.534 g/mol | logS: -5.51997 | SlogP: 3.0991 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0275814 | Sterimol/B1: 2.5543 | Sterimol/B2: 3.2851 | Sterimol/B3: 3.75412 |
Sterimol/B4: 12.8608 | Sterimol/L: 19.748 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 760.367 | Positive charged surface: 535.923 | Negative charged surface: 214.831 | Volume: 415.75 |
Hydrophobic surface: 646.141 | Hydrophilic surface: 114.226 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |