Physical Properties | | | |
Molecular Weight: 423.582 g/mol | logS: -3.91221 | SlogP: 0.1655 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0305125 | Sterimol/B1: 2.60415 | Sterimol/B2: 2.9117 | Sterimol/B3: 4.61675 |
Sterimol/B4: 6.34753 | Sterimol/L: 23.3471 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 710.802 | Positive charged surface: 476.493 | Negative charged surface: 234.309 | Volume: 386.375 |
Hydrophobic surface: 490.719 | Hydrophilic surface: 220.083 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |